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Location: On the edge of tomorrow looking back at yesterday Gender:
Posted:
Sep 13, 2026 - 9:45am
Getting ready for the end by 2035; so I have a lot of analog tools and food in my basement waiting for the drones. The clock is ticking, tic tock tic tock and the alarm is chiming. Just need a good crossbow.
I met Altman years ago (~ loopt/Y-combinator era). I got a distinctly bad vibe from him and wasn't comfortable doing business with him. I wouldn't leave him alone with a puppy, your sister, or my cocktail, and definitely keep your hand on your wallet and keep him in front of you. I wouldn't say hate, but he's not a good guy.
Chronic hatred keeps the body in a constant "fight or flight" stress response, flooding the system with cortisol and adrenaline. Over time, this ongoing state damages physical and mental health, raising the risk of high blood pressure, heart disease, weakened immunity, severe anxiety, and chronic inflammation. <1, 2, 3, 4Physical Health Effects
Nothing in law required that choice. NIH's biosecurity policy from Monday doesn't cover any of this. Arc published Thursday.
My Take
The Arc team excluded human pathogens from training data because they thought it was the right call, and no regulator or funder asked them to. That decision made by one research group in Palo Alto was the entire safety framework for what they published. NIH's policy from Monday already fails to cover what came out Thursday, and the researchers who did the work told the New York Times they have received no guidance on what they should or shouldn't build.
The next lab has no obligation to make the same choice Arc did. A group in Shenzhen or a defense contractor in Virginia could run the same method with different training data and produce something very different. Four years after a virus shut down the global economy, the U.S. regulatory response to AI-designed pathogens is that Johns Hopkins researchers are asking reporters what to do.